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|Job #: F498|
|Posted Date: September 1, 2017|
|Closes On: Open Until Filled|
|Job Title: Research Assistant II- Molecular and Cell Biology Laboratory|
|Status: Regular Full Time|
|Benefits Eligible: Yes|
|Laboratory/Department: Molecular and Cell Biology Laboratory|
|Laboratory employs the help of a small DNA virus, called adenovirus, to both understand and treat cancer. DNA viruses and tumor cells sabotage such controls to drive their respective pathological propagation, albeit with one small difference: In tumor cells the key cellular players are targeted via mutations, while in infected cells viral proteins achieve the same end. Not surprisingly, many of the cellular targets are the same. Dr. O'Shea's lab is exploiting this overlap to help address three key questions: What are the critical cellular targets and pathways that drive deregulated growth? What is the human growth deregulation program and how do we uncouple it for tumor therapy? Can we manipulate viruses as novel therapeutic agents that trigger the rapid lytic death of tumor cells but leave normal cells unharmed?|
The Research Assistant II is responsible for developing a new pipeline of virus-based oncolytic and gene therapies for the treatment of cancer and other human diseases.
This position requires constant seeing and working inside.