Part of the mission of the Salk Institute for Biological Studies is to train individuals for careers in scientific research. The expectation is that trainees will study in the many new fields developed by Institute faculty, learn the research techniques they have created, and go on to positions of leadership in other prominent scientific institutions. Postdoctoral training opportunities at the Institute are posted below.
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|Job #: F289|
|Posted Date: October 1, 2018|
|Closes On: Open Until Filled|
|Job Title: Research Associate - Regulatory Biology Laboratory, Dr. Katherine Jones|
|Status: Regular Full Time|
|Benefits Eligible: Yes|
|Laboratory/Department: Regulatory Biology Laboratory|
|Lab research focuses on gene transcription, emphasizing the role of transcription elongation and RNAPII CTD kinases in cancer and human embryonic stem cell differentiation.|
A postdoctoral position is available to study a newly-discovered pathway, which links transcription and RNAPII CTD kinases with mRNA 5-cap remodeling by mTORC1 for facilitated translation in the cytoplasm, is critical for ovarian, breast and prostate cancer metastases. The project will explore how the CDK12 kinase affects signaling under NRF2/oxidative stress conditions, as well as during human embryonic stem cell renewal and differentiation. A novel regulator of CDK12, which is essential for mitochondrial oxidative phosphorylation will also be characterized and studied for insights to inhibit this step in cancer. Prior experience with ChIP-seq,RNA-seq, imaging, and molecular and biochemical/proteomics techniques would be relevant.
PhD degree in Biological Sciences.
Recent PhD with experience with mammalian cell culture, protein biochemistry, chromatin and/or gene expression analysis including chromatin immunoprecipitation.
Application Instructions: Please email Curriculum Vitae, a statement of research interests, and three letters of reference to: email@example.com